One of the most popular places for girls to get tattoos is around the feet and ankles. It seems less of a commitment to a life long piece of art on you because it’s less noticeable and easily concealable. The feet are also not generally considered the most beautiful part of the body, so it can be a great way of making them look prettier and adding some art to them.
That's where the macrophages, the cells Henri studied, come in. They're specialized immune cells — their name means big eater in Greek — and their job is to slurp up interlopers, says Klitzman. "Macrophages can basically swallow many, many tattoo pigment particles, almost like a vacuum cleaner, just go along and suck up all those particles," he says.
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Cambodia has a rich history and very ancient temples, it also has beautiful looking characters and words. As such it has become quite popular for people to get tattooed when they travel to Cambodia. It became even more in the last decade since Hollywood actress Angelina Jolie went under the gun with a Khmer style tattoo on her back and since then many have copied this style.
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For those peeps who freak out at the commitment or thought of getting so inked, then check out this research: A small study at the University of Alabama found that those with multiple tattoos showed a better immune response to new ink than those who were going under the tattoo gun for the first time. This suggests that tattooing might stimulate the immune system, like how a vaccine does. 
According to George Orwell, coal miners could develop characteristic tattoos owing to coal dust getting into wounds.[10] This can also occur with substances like gunpowder. Similarly, a traumatic tattoo occurs when a substance such as asphalt is rubbed into a wound as the result of some kind of accident or trauma.[11] These are particularly difficult to remove as they tend to be spread across several layers of skin, and scarring or permanent discoloration is almost unavoidable depending on the location. An amalgam tattoo is when amalgam particles are implanted in to the soft tissues of the mouth, usually the gums, during dental filling placement or removal.[12] Another example of such accidental tattoos is the result of a deliberate or accidental stabbing with a pencil or pen, leaving graphite or ink beneath the skin.
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